This not a rhetorical question. As noted in  Reuters article by Kate Kelland, as we learn more about the brain, we raise challenging issues about personal responsibility. The law — an inherently conservative discipline, systemically resistant to change — is being confronted with profound questions. No doubt, some of those questions have previously been implicated by defenses of mental capacity and insanity, but these issues take on added significance as neuroscience opens our thoughts and thinking processes to more thorough examination.